Focal Mullerian duct retention in male mice with constitutively activated -catenin expression in the Mullerian duct mesenchyme
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چکیده
منابع مشابه
Symptomatic Mullerian Duct Cyst in a Male Infant
Symptomatic Mullerian duct cyst is a rare entity in children. A 9-month-old male infant presented with bowel and urinary obstructive symptoms. Imaging investigations revealed a cystic mass in the rectovesical pouch compressing bladder neck and rectum. At laparotomy, a Mullerian duct cyst was found. Most of the cyst was excised and the remaining cyst mucosa was cauterized. The child improved the...
متن کاملPersistent mullerian duct syndrome with an irreducible inguinal hernia.
Received January 2008 Accepted October 2008 INTRODUCTION Persistent mullerian duct syndrome (PMDS), or hernia uteri inguinale, describes a group of patients with a 46,XY karyotype and normal male external genitalia, but internal mullerian duct structures. Typically, these phenotypic males have unilateral or bilateral undescended testes, bilateral fallopian tubes, a uterus, and an upper vaginal ...
متن کاملPersistent mullerian duct syndrome associated with transverse testicular ectopia.
Persistent Mullerian Duct Syndrome (PMDS) associated with transverse testicular ectopia (TTE) is rare. Ten cases have been reported in the past. Accurate diagnosis with karyotype and histological analysis is crucial. Surgical management should be geared toward preservation of fertility when possible.
متن کاملPartial Müllerian Duct Retention in Smad4 Conditional Mutant Male Mice.
Müllerian duct regression is a complex process which involves the AMH signalling pathway. We have previously demonstrated that besides AMH and its specific type II receptor (AMHRII), BMPR-IA and Smad5 are two essential factors implicated in this mechanism. Mothers against decapentaplegic homolog 4 (Smad4) is a transcription factor and the common Smad (co-Smad) involved in transforming growth fa...
متن کاملPersistent Mullerian Duct Syndrome in a Post Orchideopexy Patient with Gyanaecomastia and Hypospadias: A Case Report
Persistent Mullerian Duct Syndrome (PMDS), a rare form of male pseudohermaphroditism. It is characterized by the persistence of Mullerian duct structures (uterus, fallopian tubes and upper two-thirds of vagina) in otherwise normally virilized males (Karyotype 46XY). The exact cause of PMDS is not known, however it is thought to result from the defect of the synthesis or release of Mullerian inh...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2010
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1011606107